Impact of CYP1A2 and CYP2D6 Polymorphisms on Drug Metabolism and on Insulin and Lipid Elevations and Insulin Resistance in Clozapine-Treated Patients - Concepedia

Concepedia

Publication | Closed Access

Impact of CYP1A2 and CYP2D6 Polymorphisms on Drug Metabolism and on Insulin and Lipid Elevations and Insulin Resistance in Clozapine-Treated Patients

66

Citations

0

References

2007

Year

Kristina Melkersson, M.G. Scordo, Arzu Gunes, Marja‐Liisa Dahl

The Journal of Clinical Psychiatry

Abstract

CYP1A2 variants *1C and *1D seem to be associated with higher serum clozapine concentrations and an increased risk of developing insulin and lipid elevations and insulin resistance on a given dose of clozapine.