Concepedia

Mutagenicity of carcinogenic methylating agents is associated with a specific DNA modification

Robert F. Newbold, William Warren, A.S.C. Medcalf, J. Amos

Nature · 1980 · 232 citations · 20 references

DOI

Concepts

References

20

Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

A. Loveless · Nature · 1969 · 948 citations

, , +14

Genetic studies of the lac repressor

Christine Coulondre, Jeffrey H Miller · Journal of Molecular Biology · 1977 · 605 citations

, , +3

Methylation of deoxyribonucleic acid in cultured mammalian cells by <i>N</i>-methyl-<i>N</i>′-nitro-<i>N</i>-nitrosoguanidine. The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation

P.D. Lawley, Carolyn J. Thatcher · Biochemical Journal · 1970 · 495 citations · Full text

, , +10

All oxygens in nucleic acids react with carcinogenic ethylating agents

Brett C. Singer · Nature · 1976 · 310 citations

, , +11

Exceptional mutagenicity of a benzo[a]pyrene diol epoxide in cultured mammalian cells

Robert F. Newbold, P. Brookes · Nature · 1976 · 270 citations

, , +14