Exceptional mutagenicity of a benzo[a]pyrene diol epoxide in cultured mammalian cells

Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide

Peter Sims, P.L. Grover, Alan Swaisland et al. · Nature · 1974 · 1.1K citations

Life Sciences, Biochemistry, Metabolism +12

Evidence for the Binding of Polynuclear Aromatic Hydrocarbons to the Nucleic Acids of Mouse Skin : Relation between Carcinogenic Power of Hydrocarbons and their Binding to Deoxyribonucleic Acid

P. Brookes, P.D. Lawley · Nature · 1964 · 678 citations

Pharmacy, Molecular Biology, Toxicology +17

A comparison of the 8-azaguanine and ouabain-resistance systems for the selection of induced mutant Chinese hamster cells

C.F. Arlett, Duncan Turnbull, Susan A. Harcourt et al. · Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis · 1975 · 157 citations

Medicine, Genetics, Mutation Breeding +7

ENZYMATIC HYDROXYLATION OF BENZOPYRENE AND ITS RELATIONSHIP TO CYTOTOXICITY

Harry V. Gelboin, Eliezer Huberman, Leo Sachs · Proceedings of the National Academy of Sciences · 1969 · 136 citations · Full text

Life Sciences, Biochemistry, Toxicology +17

Mutation induction and inactivation in mammalian cells exposed to ionising radiation

John Thacker, Roger Cox · Nature · 1975 · 103 citations

Medicine, Genetics, Radiation Oncology +14