P.D. Lawley

Evidence for the Binding of Polynuclear Aromatic Hydrocarbons to the Nucleic Acids of Mouse Skin : Relation between Carcinogenic Power of Hydrocarbons and their Binding to Deoxyribonucleic Acid

P. Brookes, P.D. Lawley · Nature · 1964 · 678 citations

Biochemistry, Oncogenic Agent, Natural Sciences +10

Methylation of deoxyribonucleic acid in cultured mammalian cells by <i>N</i>-methyl-<i>N</i>′-nitro-<i>N</i>-nitrosoguanidine. The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation

P.D. Lawley, Carolyn J. Thatcher · Biochemical Journal · 1970 · 495 citations · Full text

Cellular Thiol Concentrations, Epigenetic Change, Dna Methylation +24

Interstrand cross-linking of DNA by difunctional alkylating agents

P.D. Lawley, P. Brookes · Journal of Molecular Biology · 1967 · 278 citations

Cross-link, Natural Sciences, Oligonucleotide +3

Molecular Mechanism of the Cytotoxic Action of Difunctional Alkylating Agents and of Resistance to this Action

P.D. Lawley, P. Brookes · Nature · 1965 · 255 citations

Cytotoxic Action, Drug Resistance Analysis, Biochemistry +10

The reaction of mustard gas with nucleic acids <i>in vitro</i> and <i>in vivo</i>

P. Brookes, P.D. Lawley · Biochemical Journal · 1960 · 226 citations · Full text

Mustard Gas, Nucleic Acid Chemistry, Biochemistry +7