EZH2 Inhibitor Efficacy in Non-Hodgkin’s Lymphoma Does Not Require Suppression of H3K27 Monomethylation

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

Ash A. Alizadeh, Michael B. Eisen, R. Eric Davis et al. · Nature · 2000 · 10K citations

Life Sciences, Molecular Biology, Oncology +12

The Use of Molecular Profiling to Predict Survival after Chemotherapy for Diffuse Large-B-Cell Lymphoma

Andreas Rosenwald, George W. Wright, Wing C. Chan et al. · New England Journal of Medicine · 2002 · 3.9K citations · Full text

Medicine, Molecular Biology, Oncology +16

Discovery and saturation analysis of cancer genes across 21 tumour types

Michael S. Lawrence, Petar Stojanov, Craig H. Mermel et al. · Nature · 2014 · 3.2K citations · Full text

Medicine, Bioinformatics, Oncology +16

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

Andrew J. Souers, Joel D. Leverson, Erwin R. Boghaert et al. · Nature Medicine · 2013 · 3K citations

Medicine, Oncology, Pharmacology +10

The polycomb group protein EZH2 is involved in progression of prostate cancer

Sooryanarayana Varambally, Saravana M. Dhanasekaran, Ming Zhou et al. · Nature · 2002 · 2.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +14