Charlie Hatton

Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma

Rameen Beroukhim, Gad Getz, Leia Nghiemphu et al. · Proceedings of the National Academy of Sciences · 2007 · 1.1K citations · Full text

Life Sciences, Genetics, Oncology +17

High-throughput oncogene mutation profiling in human cancer

Roman K. Thomas, Alissa C. Baker, Ralph DeBiasi et al. · Nature Genetics · 2007 · 996 citations

Medicine, Molecular Biology, Oncology +14

Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway

Courtney A. Lovejoy, Wen‐Di Li, Steven Reisenweber et al. · PLoS Genetics · 2012 · 638 citations · Full text

Life Sciences, Genetics, Oncology +17

A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia

Andrei V. Krivtsov, Kathryn Evans, Jayant Y. Gadrey et al. · Cancer Cell · 2019 · 449 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +14

Drug-sensitive <i>FGFR2</i> mutations in endometrial carcinoma

Amit Dutt, Helga B. Salvesen, Tzu-Hsiu Chen et al. · Proceedings of the National Academy of Sciences · 2008 · 345 citations · Full text

Medicine, Cancer Biology, Oncology +17