Concepedia

Publication | Closed Access

Alloimmunity in Primate Heart Recipients with CD154 Blockade: Evidence for Alternative Costimulation Mechanisms

DOI

42

Citations

41

References

2006

Year

Agnes M. Azimzadeh, Steffen Pfeiffer, Guosheng Wu, Carsten Schr der, George L. Zorn, Shahrooz S. Kelishadi, Engin Özkaynak, Marilyn R. Kehry, James B. Atkinson, Geraldine G. Miller,
Transplantation

Abstract

CD154 monotherapy modulates primate cardiac alloimmunity, but does not readily induce tolerance. Targeting alternative costimulation pathways, including ICOS, may facilitate tolerance induction based on CD154 blockade.

References

YearCitations

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