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Reduced Expression of FOXP3 and Regulatory T-Cell Function in Severe Forms of Early-onset Autoimmune Enteropathy

Nicolette Moes, Frédéric Rieux‐Laucat, Bernadette Bègue, Julien Verdier, Bénédicte Neven, Natacha Patey, Troy Torgerson, Capucine Pïcard, Marie‐Claude Stolzenberg, Corinne Ruemmele,

Gastroenterology · 2010 · 105 citations · 22 references

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22

Control of Regulatory T Cell Development by the Transcription Factor <i>Foxp3</i>

Shohei Hori, Takashi Nomura, Shimon Sakaguchi · Science · 2003 · 8.1K citations

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Jason D. Fontenot, Marc A. Gavin, Alexander Y. Rudensky · Nature Immunology · 2003 · 7.7K citations

, , +14

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

Craig L. Bennett, Jacinda R. Christie, Fred Ramsdell et al. · Nature Genetics · 2001 · 3.4K citations

, , +13

An essential role for Scurfin in CD4+CD25+ T regulatory cells

Roli Khattri, Tom Cox, Sue-Ann Yasayko et al. · Nature Immunology · 2003 · 2.8K citations

, , +9

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

Robert S. Wildin, Fred Ramsdell, Jane Peake et al. · Nature Genetics · 2001 · 1.9K citations

, , +17