Concepedia

Synthesis and structure–Activity relationships of 2-Amino-8-hydroxyadenines as orally active interferon inducing agents

Ayumu Kurimoto, Tetsuhiro Ogino, Shinji Ichii, Yoshiaki Isobe, Masanori Tobe, Haruhisa Ogita, Haruo Takaku, Hironao Sajiki, Kosaku Hirota, Hajime Kawakami

Bioorganic & Medicinal Chemistry · 2003 · 36 citations · 17 references

DOI

Concepts

References

17

Small anti-viral compounds activate immune cells via the TLR7 MyD88–dependent signaling pathway

Hiroaki Hemmi, Tsuneyasu Kaisho, Osamu Takeuchi et al. · Nature Immunology · 2002 · 2.5K citations

, , +16

The interferon system. A bird's eye view of its biochemistry.

Ganes C. Sen, Péter Lengyel · Journal of Biological Chemistry · 1992 · 633 citations · Full text

, , +8

Resistance to Recombinant Interferon Alfa-2a in Hairy-Cell Leukemia Associated with Neutralizing Anti-Interferon Antibodies

Ronald G. Steis, John W. Smith, Walter J. Urba et al. · New England Journal of Medicine · 1988 · 246 citations

, , +15

Cytokine induction in mice by the immunomodulator imiquimod

Michael J. Reiter, Traci L Tester man, Richard L. Miller et al. · Journal of Leukocyte Biology · 1994 · 171 citations

, , +12

Tilorone Hydrochloride: Mode of Action

Gerald D. Mayer, Russell F. Krueger · Science · 1970 · 139 citations

, , +11