Concepedia

Activation of β2-adrenergic receptor stimulates γ-secretase activity and accelerates amyloid plaque formation

Yanxiang Ni, Xiaohui Zhao, Guobin Bao, Lin Zou, Lin Teng, Zhu Wang, Min Song, Jiaxiang Xiong, Yun Bai, Gang Pei

Nature Medicine · 2006 · 238 citations · 37 references

DOI

Concepts

References

37

β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE

Robert Vassar, Brian D. Bennett, Safura Babu‐Khan et al. · Science · 1999 · 3.8K citations · Full text

, , +17

Natural oligomers of the amyloid-β protein specifically disrupt cognitive function

James Cleary, Dominic M. Walsh, J. Hofmeister et al. · Nature Neuroscience · 2004 · 1.7K citations

, , +16

A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

Sascha Weggen, Jason L. Eriksen, Pritam Das et al. · Nature · 2001 · 1.4K citations

, , +14

A mechanism converting psychosocial stress into mononuclear cell activation

Angelika Bierhaus, Jutta M. Wolf, Martin Andrassy et al. · Proceedings of the National Academy of Sciences · 2003 · 920 citations · Full text

, , +17

Release of Alzheimer Amyloid Precursor Derivatives Stimulated by Activation of Muscarinic Acetylcholine Receptors

Roger M. Nitsch, Barbara E. Slack, Richard J. Wurtman et al. · Science · 1992 · 899 citations

, , +17