Concepedia

Inflammation-driven carcinogenesis is mediated through STING

Jeonghyun Ahn, Tianli Xia, Hiroyasu Konno, K Konno, Phillip Ruiz, Glen N. Barber

Nature Communications · 2014 · 439 citations · 15 references

DOIFull text

Open access

Concepts

References

15

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

Lijun Sun, Jiaxi Wu, Fenghe Du et al. · Science · 2012 · 4.8K citations

, , +16

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Hiroki Ishikawa, Glen N. Barber · Nature · 2008 · 3.5K citations · Full text

, , +12

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

Hiroki Ishikawa, Zhe Ma, Glen N. Barber · Nature · 2009 · 2.7K citations · Full text

, , +14

Langerhans cells renew in the skin throughout life under steady-state conditions

Miriam Mérad, Markus G. Manz, Holger Karsunky et al. · Nature Immunology · 2002 · 937 citations · Full text

, , +12

Mice deficient in tumor necrosis factor-α are resistant to skin carcinogenesis

Robert J. Moore, David M. Owens, Gordon Stamp et al. · Nature Medicine · 1999 · 836 citations

, , +12