Concepedia

Chemical Proteomics Identifies Nampt as the Target of CB30865, An Orphan Cytotoxic Compound

Tracey C. Fleischer, Brett R. Murphy, Jeffrey S. Flick, Ryan T. Terry-Lorenzo, Zhong-Hua Gao, Thaylon Davis, Rena McKinnon, Kirill Ostanin, J. Adam Willardsen, J. Jay Boniface

Chemistry & Biology · 2010 · 53 citations · 18 references

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18

An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

Jimmy K. Eng, Ashley L. McCormack, John R. Yates · Journal of the American Society for Mass Spectrometry · 1994 · 6.6K citations

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Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor.

Babru Samal, Y. Sun, George Stearns et al. · Molecular and Cellular Biology · 1994 · 962 citations · Full text

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Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis

Anthony Rongvaux, Robin J. Shea, Martha H. Mulks et al. · European Journal of Immunology · 2002 · 543 citations

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The pharmacokinetics, toxicities, and biologic effects of FK866, a nicotinamide adenine dinucleotide biosynthesis inhibitor

Kyle D. Holen, Leonard B. Saltz, Ellen Hollywood et al. · Investigational New Drugs · 2007 · 292 citations

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Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents

Javed Khan, Xiao Tao, Liang Tong · Nature Structural & Molecular Biology · 2006 · 260 citations

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