Javed Khan

Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165

Stephen T. Wrobleski, Ryan Moslin, Shuqun Lin et al. · Journal of Medicinal Chemistry · 2019 · 345 citations · Full text

Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents

Javed Khan, Xiao Tao, Liang Tong · Nature Structural & Molecular Biology · 2006 · 259 citations

Human Nmprtase, Medicinal Chemistry, Drug Target +12

Crystal Structure of the Toll/Interleukin-1 Receptor Domain of Human IL-1RAPL

Javed Khan, Elizabeth Brint, Luke O'neill et al. · Journal of Biological Chemistry · 2004 · 132 citations · Full text

Camel Lactoferrin, a Transferrin-cum-Lactoferrin: Crystal Structure of Camel Apolactoferrin at 2.6Å Resolution and Structural Basis of its Dual Role

Javed Khan, Pravindra Kumar, M. Paramasivam et al. · Journal of Molecular Biology · 2001 · 94 citations

Crystal Structure, Bioorganic Chemistry, Biochemistry +6

Conserved Surface Features Form the Double-stranded RNA Binding Site of Non-structural Protein 1 (NS1) from Influenza A and B Viruses

Cuifeng Yin, Javed Khan, G.V.T. Swapna et al. · Journal of Biological Chemistry · 2007 · 92 citations · Full text

Combined Nmr, Virus Structure, Viral Replication +12