Rena McKinnon

The Human Endosomal Sorting Complex Required for Transport (ESCRT-I) and Its Role in HIV-1 Budding

Melissa D. Stuchell, Jennifer Garrus, Bárbara Müller et al. · Journal of Biological Chemistry · 2004 · 173 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +16

Characterization of the Cellular and Antitumor Effects of MPI-0479605, a Small-Molecule Inhibitor of the Mitotic Kinase Mps1

Keith D. Tardif, Aaron Rogers, Jared Cassiano et al. · Molecular Cancer Therapeutics · 2011 · 94 citations · Full text

Life Sciences, Cancer Biology, Oncology +17

Chemical Proteomics Identifies Nampt as the Target of CB30865, An Orphan Cytotoxic Compound

Tracey C. Fleischer, Brett R. Murphy, Jeffrey S. Flick et al. · Chemistry & Biology · 2010 · 53 citations · Full text

Life Sciences, Biochemistry, Pharmacology +12

Discovery of (2<i>S</i>)-1-[4-(2-{6-Amino-8-[(6-bromo-1,3-benzodioxol-5-yl)sulfanyl]-9<i>H</i>-purin-9-yl}ethyl)piperidin-1-yl]-2-hydroxypropan-1-one (MPC-3100), a Purine-Based Hsp90 Inhibitor

Seho Kim, Ashok C. Bajji, Rajendra Tangallapally et al. · Journal of Medicinal Chemistry · 2012 · 43 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Lead optimization of purine based orally bioavailable Mps1 (TTK) inhibitors

Dhiraj Kumar, Christophe Hoarau, Matthew G. Bursavich et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 34 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14