Protective effects of curcumin against hepatic fibrosis induced by carbon tetrachloride: Modulation of high-mobility group box 1, Toll-like receptor 4 and 2 expression

HMG-1 as a Late Mediator of Endotoxin Lethality in Mice

Haichao Wang, Ona Bloom, Minghuang Zhang et al. · Science · 1999 · 3.4K citations

TLR4 enhances TGF-β signaling and hepatic fibrosis

Ekihiro Seki, Samuele De Minicis, Christoph H. Österreicher et al. · Nature Medicine · 2007 · 1.9K citations

Inflammation, Fibrosis, Hepatology +11

Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion

Tiziana Bonaldi · The EMBO Journal · 2003 · 1.2K citations · Full text

Chromatin, Protein Secretion, Cell Regulation +8

High mobility group box 1 protein interacts with multiple Toll-like receptors

Jong Sung Park, Fabia Gamboni-Robertson, Qianbin He et al. · American Journal of Physiology-Cell Physiology · 2005 · 931 citations

Innate Immune System, Immunology, Inflammation +17

Toll–Like Receptor 4 Mediates Inflammatory Signaling by Bacterial Lipopolysaccharide in Human Hepatic Stellate Cells

Yong‐Han Paik, Robert F. Schwabe, Ramón Bataller et al. · Hepatology · 2003 · 639 citations · Full text