The use of short-term tests to measure the preventive action of reducing agents on formation and activation of carcinogenic nitroso compounds

Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection

Bruce N. Ames, William E. Durston, Edith F. Yamasaki et al. · Proceedings of the National Academy of Sciences · 1973 · 2.3K citations · Full text

Pharmacy, Molecular Biology, Toxicology +17

Ascorbate-Nitrite Reaction: Possible Means of Blocking the Formation of Carcinogenic <i>N</i> -Nitroso Compounds

Sidney S. Mirvish, Lawrence Wallcave, Michael Eagen et al. · Science · 1972 · 500 citations

Medicine, Pharmacology, Toxicology +13

Liver microsomal metabolism of aflatoxin B 1 to a reactive derivative toxic to Salmonella typhimurium TA 1530.

R. Colin Garner, Elizabeth C. Miller, James A. Miller · PubMed · 1972 · 410 citations

Life Sciences, Microbiology, Toxicology +13

Toxic liver injury and carcinogenesis. Methylation of rat-liver nucleic acids by dimethylnitrosamine <i>in vivo</i>

PN MAGEE, Emmanuel Farber · Biochemical Journal · 1962 · 398 citations · Full text

Pharmacy, Molecular Biology, Toxicology +11

Dimethylnitrosamine: formation of mutagenic compounds by interaction with mouse liver microsomes

H.‐J. Malling · Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis · 1971 · 266 citations

Pharmacy, Toxicology, Biochemical Toxicology +12