Concepedia

Nitrosamine Carcinogenesis

Nitrosamine Carcinogenesis is a chemical carcinogenesis process in which nitrosamines—organic compounds containing a nitroso group bonded to an amine—induce cancer through DNA alkylation and mutagenic adduct formation, distinguishing it from other carcinogenic pathways by its specific reliance on N-nitroso chemical activation.

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49.7K

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3K

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710

Institutions

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2017–2026

50

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Publications

1.1K

Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

A. Loveless · Nature · 1969 · 948 citations

, , +14

Nitrosamines as Environmental Carcinogens

William Lijinsky, Samuel S. Epstein · Nature · 1970 · 674 citations

, , +12

Biochemical characterisation of stages of hepatocarcinogenesis after a single dose of diethylnitrosamine

Henry C. Pitot, Lona Barsness, Tom Goldsworthy et al. · Nature · 1978 · 412 citations

, , +14

Nitrosamine-induced carcinogenesis. The alkylation of nucleic acids of the rat by <i>N</i>-methyl-<i>N</i>-nitrosourea, dimethylnitrosamine, dimethyl sulphate and methyl methanesulphonate

Peter Swann, Peter Magee · Biochemical Journal · 1968 · 373 citations · Full text

, , +12

Inhibition of tobacco-specific nitrosamine-induced lung tumorigenesis in A/J mice by green tea and its major polyphenol as antioxidants

Lung Cancer · 1993 · 348 citations

, , +15

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Authors

3K

  1. SS
    Stephen S. Hecht

    University of Minnesota, United States

    75 publications · 5K citations

    39

    h-index

  2. SF
    Shoji Fukushima

    Osaka City University, Japan

    68 publications · 2.6K citations

    31

    h-index

  3. NI
    Nobuyuki Ito

    Nagoya City University, Japan

    37 publications · 1.6K citations

    23

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  4. WL
    William Lijinsky

    Cancer Research Center, United States

    30 publications · 1.8K citations

    21

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  5. SA
    Shantu Amin

    Pennsylvania State University, United States

    22 publications · 1.8K citations

    19

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1–5 of 3K

Institutions

710

  1. Institute for Cancer Prevention

    Valhalla, United States

    35 h-index

    165 publications

    9.1K citations

  2. Nagoya City University

    Nagoya, Japan

    33 h-index

    366 publications

    13K citations

  3. National Institutes of Health

    Bethesda, United States

    27 h-index

    122 publications

    9.8K citations

  4. Dana (United States)

    Maumee, United States

    23 h-index

    78 publications

    3.7K citations

  5. University of Minnesota

    Minneapolis, United States

    22 h-index

    143 publications

    5.7K citations

  6. National Cancer Institute

    Bethesda, United States

    21 h-index

    79 publications

    3.5K citations

  7. Mizuho (Japan)

    Tokyo, Japan

    20 h-index

    175 publications

    5.7K citations

  8. Nara Medical University

    Kashihara-shi, Japan

    19 h-index

    117 publications

    4.3K citations

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Venues

  1. PubMed

    Repository · 258 publications · 13.3K citations

    59

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  2. Carcinogenesis

    143 publications · 5.9K citations

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  3. JNCI Journal of the National Cancer Institute

    54 publications · 2.5K citations

    28

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  4. Cancer Letters

    68 publications · 2.2K citations

    28

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  5. Japanese Journal of Cancer Research

    32 publications · 1.1K citations

    20

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