Concepedia

Differential formation of prostacyclin (PGX or PGI2) by layers of the arterial wall. An explanation for the anti-thrombotic properties of vascular endothelium

Salvador Moncada, A.G. Herman, E.A. Higgs, John R. Vane

Thrombosis Research · 1977 · 684 citations · 36 references

DOI

Concepts

References

36

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

Salvador Moncada, Ryszard J. Gryglewski, S Bunting et al. · Nature · 1976 · 3.6K citations

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Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.

Mats Hámberg, Jan Olof Svensson, B Samuelsson · Proceedings of the National Academy of Sciences · 1975 · 3.1K citations · Full text

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Free-radical mechanisms in tissue injury

T. F. Slater · Biochemical Journal · 1984 · 1.5K citations · Full text

, , +11

Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides

Ryszard J. Gryglewski, Stuart Bunting, Salvador Moncada et al. · Prostaglandins · 1976 · 1K citations

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Isolation and Structure of Two Prostaglandin Endoperoxides That Cause Platelet Aggregation

Mats Hámberg, Jan Svensson, Toshio Wakabayashi et al. · Proceedings of the National Academy of Sciences · 1974 · 998 citations · Full text

, , +10