Concepedia

Structure-based design, synthesis, and nonalcoholic steatohepatitis (NASH)-preventive effect of phenylpropanoic acid peroxisome proliferator-activated receptor (PPAR) α-selective agonists

Shintaro Ban, Jun-ichi Kasuga, Izumi Nakagome, Hiromi Nobusada, Fusako Takayama, Shuichi Hirono, Hiromu Kawasaki, Yuichi Hashimoto, Hiroyuki Miyachi

Bioorganic & Medicinal Chemistry · 2011 · 16 citations · 13 references

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References

13

The peroxisome proliferator-activated receptor:retinoid X receptor heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs

Isabelle Issemann, Rebecca A. Prince, J. D. Tugwood et al. · Journal of Molecular Endocrinology · 1993 · 305 citations

, , +12

Diagnosis and interpretation of steatosis and steatohepatitis.

Alastair D. Burt, Adrienne Mutton, Chris Day · PubMed · 1998 · 292 citations

, , +10

Influence of TNF gene polymorphisms in Japanese patients with NASH and simple steatosis

Katsutoshi Tokushige, Mihoko Takakura, Noriko Tsuchiya-Matsushita et al. · Journal of Hepatology · 2007 · 149 citations

, , +16

Role of PPAR in the Pharmacological Regulation of Lipoprotein Metabolism by Fibrates and Thiazolidinediones

Bart Staels, Johan Auwerx · Current Pharmaceutical Design · 1997 · 83 citations · Full text

, , +16

A systematic analytical chemistry/cell assay approach to isolate activators of orphan nuclear receptors from biological extracts: characterization of peroxisome proliferator-activated receptor activators in plasma

CD Banner, Martin Göttlicher, E Widmark et al. · Journal of Lipid Research · 1993 · 76 citations · Full text

, , +14