Hiromi Nobusada

Design and synthesis of a series of α-benzyl phenylpropanoic acid-type peroxisome proliferator-activated receptor (PPAR) gamma partial agonists with improved aqueous solubility

Masao Ōhashi, Takuji Oyama, Endy Widya Putranto et al. · Bioorganic & Medicinal Chemistry · 2013 · 33 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Design, Synthesis, and Structural Analysis of Phenylpropanoic Acid-Type PPARγ-Selective Agonists: Discovery of Reversed Stereochemistry−Activity Relationship

Masao Ōhashi, Takuji Oyama, Izumi Nakagome et al. · Journal of Medicinal Chemistry · 2010 · 24 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure-based design, synthesis, and nonalcoholic steatohepatitis (NASH)-preventive effect of phenylpropanoic acid peroxisome proliferator-activated receptor (PPAR) α-selective agonists

Shintaro Ban, Jun-ichi Kasuga, Izumi Nakagome et al. · Bioorganic & Medicinal Chemistry · 2011 · 16 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Design, synthesis and in vitro evaluation of a series of α-substituted phenylpropanoic acid PPARγ agonists to further investigate the stereochemistry–activity relationship

Masao Ōhashi, Izumi Nakagome, Jun-ichi Kasuga et al. · Bioorganic & Medicinal Chemistry · 2012 · 13 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16