MCAM, as a novel receptor for S100A8/A9, mediates progression of malignant melanoma through prominent activation of NF-κB and ROS formation upon ligand binding

I Made Winarsa Ruma, Endy Widya Putranto, Eisaku Kondo, +14

Clinical & Experimental Metastasis

Tumor BiologyNovel ReceptorMedicineMelanomaImmunology +8

Dramatic Increase in Expression of a Transgene by Insertion of Promoters Downstream of the Cargo Gene

Masakiyo Sakaguchi, Masami Watanabe, Rie Kinoshita, +12

Molecular Biotechnology

Stromal mesenchymal stem cells facilitate pancreatic cancer progression by regulating specific secretory molecules through mutual cellular interaction

Ken Saito, Masakiyo Sakaguchi, Satoshi Maruyama, +7

Journal of Cancer

Critical role of the MCAM-ETV4 axis triggered by extracellular S100A8/A9 in breast cancer aggressiveness

Youyi Chen, I Wayan Sumardika, Nahoko Tomonobu, +24

Neoplasia

Identification of an S100A8 Receptor Neuroplastin-β and its Heterodimer Formation with EMMPRIN

Masakiyo Sakaguchi, Mami Yamamoto, Masashi Miyai, +11

Journal of Investigative Dermatology

Signal TransductionMolecular NeuroscienceHeterodimer FormationS100a8 Receptor Neuroplastin-βReceptor (Biochemistry) +5

Newly developed anti‐S100A8/A9 monoclonal antibody efficiently prevents lung tropic cancer metastasis

Rie Kinoshita, Hiroki Sato, Akira Yamauchi, +24

International Journal of Cancer

Melanoma cell adhesion molecule is the driving force behind the dissemination of melanoma upon S100A8/A9 binding in the original skin lesion

Youyi Chen, I Wayan Sumardika, Nahoko Tomonobu, +23

Cancer Letters

S100a8/a9 BindingCell AdhesionImmunologyDermatologyCancer Biology +16

DNAX-activating Protein 10 (DAP10) Membrane Adaptor Associates with Receptor for Advanced Glycation End Products (RAGE) and Modulates the RAGE-triggered Signaling Pathway in Human Keratinocytes

Masakiyo Sakaguchi, Hitoshi Murata, Yumi Aoyama, +11

Journal of Biological Chemistry

ImmunologyMolecular BiologyCell DeathRage-triggered Signaling PathwayCellular Physiology +17

Extract of Cordyceps militaris inhibits angiogenesis and suppresses tumor growth of human malignant melanoma cells

I Made Winarsa Ruma, Endy Widya Putranto, Eisaku Kondo, +8

International Journal of Oncology

Neuroplastin‐β mediates S100A8/A9‐induced lung cancer disseminative progression

I Wayan Sumardika, Youyi Chen, Nahoko Tomonobu, +18

Molecular Carcinogenesis

Cancer ImmunosurveillanceSignaling PathwayAtopic DermatitisCell SignalingMedicine +11