Differential association of the PTPN22 coding variant with autoimmune diseases in a Dutch population

A Missense Single-Nucleotide Polymorphism in a Gene Encoding a Protein Tyrosine Phosphatase (PTPN22) Is Associated with Rheumatoid Arthritis

Ann B. Begovich, Victoria Carlton, Lee Honigberg et al. · The American Journal of Human Genetics · 2004 · 1.5K citations · Full text

Rheumatoid Disorder, Rheumatology, Protein Tyrosine Phosphatase +13

A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

Nunzio Bottini, Lucia Musumeci, Andrés Alonso et al. · Nature Genetics · 2004 · 1.4K citations · Full text

Lymphoid Tyrosine Phosphatase, Metabolic Syndrome, Autoimmune Disease +9

Genetic Association of the R620W Polymorphism of Protein Tyrosine Phosphatase PTPN22 with Human SLE

Chieko Kyogoku, Ward Ortmann, Annette Lee et al. · The American Journal of Human Genetics · 2004 · 658 citations · Full text

Signal Transduction, Genetic Disorder, Genetics +11

Replication of an Association Between the Lymphoid Tyrosine Phosphatase Locus (<i>LYP/PTPN22</i>) With Type 1 Diabetes, and Evidence for Its Role as a General Autoimmunity Locus

Deborah J. Smyth, Jason D. Cooper, J Collins et al. · Diabetes · 2004 · 492 citations

The Codon 620 Tryptophan Allele of the Lymphoid Tyrosine Phosphatase (LYP) Gene Is a Major Determinant of Graves’ Disease

Marija Velaga, Valerie Wilson, Claire Jennings et al. · The Journal of Clinical Endocrinology & Metabolism · 2004 · 460 citations · Full text