Localization of Rheb to the endomembrane is critical for its signaling function

Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex

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Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton

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Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

Ken Inoki, Yong Li, Tian Xu et al. · Genes & Development · 2003 · 1.9K citations · Full text

Life Sciences, Cell Biology, Genetics +15

Tuberous Sclerosis Complex Gene Products, Tuberin and Hamartin, Control mTOR Signaling by Acting as a GTPase-Activating Protein Complex toward Rheb

Andrew R. Tee, Brendan D. Manning, Philippe P. Roux et al. · Current Biology · 2003 · 1.2K citations · Full text

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A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

John F. Hancock, Hugh Paterson, Christopher J. Marshall · Cell · 1990 · 1.1K citations

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