A simple, green and one-pot four-component synthesis of 1,4-dihydropyridines and their aromatization

Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism.

F. Peter Guengerich, M V Martin, Philippe Beaune et al. · Journal of Biological Chemistry · 1986 · 730 citations · Full text

Medicine, Biochemistry, Pharmacology +17

A Highly Enantioselective Brønsted Acid Catalyzed Cascade Reaction: Organocatalytic Transfer Hydrogenation of Quinolines and their Application in the Synthesis of Alkaloids

Magnus Rueping, Andrey P. Antonchick, Thomas Theissmann · Angewandte Chemie International Edition · 2006 · 724 citations

Natural Sciences, Chemistry, Medicinal Chemistry +14

Oxidation of 4-aryl- and 4-alkyl-substituted 2,6-dimethyl-3,5-bis(alkoxycarbonyl)-1,4-dihydropyridines by human liver microsomes and immunochemical evidence for the involvement of a form of cytochrome P-450

Ronald Boecker, F. Peter Guengerich · Journal of Medicinal Chemistry · 1986 · 323 citations · Full text

Medicine, Biochemistry, Pharmacology +13

Oxidative Aromatization of 1,3,5-Trisubstituted Pyrazolines and Hantzsch 1,4-Dihydropyridines by Pd/C in Acetic Acid

Natsuki Nakamichi, Yuka Kawashita, Masahiko Hayashi · Organic Letters · 2002 · 251 citations

Natural Sciences, Chemical Engineering, Chemistry +12

An efficient and one-pot synthesis of imidazolines and benzimidazoles via anaerobic oxidation of carbon–nitrogen bonds in water

Pranjal Gogoi, Dilip Konwar · Tetrahedron Letters · 2005 · 233 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8