The Role of Lysosomes in the Cellular Distribution of Thioridazine and Potential Drug Interactions

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

S Ohkuma, Brian D. Poole · Proceedings of the National Academy of Sciences · 1978 · 2.2K citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

The effect of selective serotonin re‐uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes.

H.K. Crewe, MS Lennard, GT Tucker et al. · British Journal of Clinical Pharmacology · 1992 · 471 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Dose-dependent inhibition of CYP1A2, CYP2C19 and CYP2D6 by citalopram, fluoxetine, fluvoxamine and paroxetine

U. Jeppesen, L. F. Gram, Kirsten Vistisen et al. · European Journal of Clinical Pharmacology · 1996 · 321 citations

Medicine, Pharmacokinetics, Pharmacology +12

Changes in Lipid Structure Produced by Surfactant Proteins SP-A, SP-B, and SP-C

Mary C. Williams, Samuel Hawgood, Robert L. Hamilton · American Journal of Respiratory Cell and Molecular Biology · 1991 · 210 citations

Life Sciences, Biochemistry, Biology +16

Tricyclic Antidepressants in Depressed Patients With Cardiac Conduction Disease

Steven P. Roose · Archives of General Psychiatry · 1987 · 157 citations

Medicine, Cardiology, Pharmacology +15