Glucocorticoid Receptor Status Is a Principal Determinant of Variability in the Sensitivity of Non–Small-Cell Lung Cancer Cells to Pemetrexed

Phase III Study Comparing Cisplatin Plus Gemcitabine With Cisplatin Plus Pemetrexed in Chemotherapy-Naive Patients With Advanced-Stage Non–Small-Cell Lung Cancer

Giorgio V. Scagliotti, Purvish Parikh, Joachim von Pawel et al. · Journal of Clinical Oncology · 2008 · 3.2K citations

Medicine, Oncology, Pharmacology +16

Randomized Phase III Trial of Pemetrexed Versus Docetaxel in Patients With Non–Small-Cell Lung Cancer Previously Treated With Chemotherapy

Nasser H. Hanna, Frances A. Shepherd, Frank V. Fossella et al. · Journal of Clinical Oncology · 2004 · 2.4K citations · Full text

Medicine, Oncology, Pharmacology +15

Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomised, double-blind, phase 3 study

Tudor–Eliade Ciuleanu, Thomas Brodowicz, Christoph Zielinski et al. · The Lancet · 2009 · 1.1K citations · Full text

Medicine, Oncology, Pharmacotherapy +14

Expression and Subcellular Distribution of the β-Isoform of the Human Glucocorticoid Receptor*

Robert H. Oakley, Jeffrey C. Webster, Madhabananda Sar et al. · Endocrinology · 1997 · 193 citations

Life Sciences, Biochemistry, Molecular Biology +13

Multiple folate enzyme inhibition: mechanism of a novel pyrrolopyrimidine-based antifolate LY231514 (MTA)

Chuan Shih, Lillian L. Habeck, Laurane G. Mendelsohn et al. · Advances in Enzyme Regulation · 1998 · 144 citations

Life Sciences, Biochemistry, Pharmacology +12