<i>PAX8-PPAR</i>γ Rearrangement Is Frequently Detected in the Follicular Variant of Papillary Thyroid Carcinoma

Abstract

We conclude that a subset of FVPTC shares some of the molecular features of follicular tumors. Further studies are necessary to clarify the putative clinical significance (e.g. association to blood-born metastases) of PAX8-PPARgamma rearrangement, RAS mutations, and BRAF(K601E) in FVPTCs.