Structure–activity relationship (SAR) studies of quinoxalines as novel HCV NS5B RNA-dependent RNA polymerase inhibitors

Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

Qui‐Lim Choo, George Kuo, Amy J. Weiner et al. · Science · 1989 · 6.9K citations

Vaccination, Viral Replication, Nanbh Agent +15

Natural history of liver fibrosis progression in patients with chronic hepatitis C

Thierry Poynard, Pierre Bédossa, P Opolon · The Lancet · 1997 · 3K citations

Liver Fibrosis Progression, Hepatology, Hepatitis C +11

Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus.

Sven‐Erik Behrens, Licia Tomei, Raffaele De Francesco · The EMBO Journal · 1996 · 683 citations · Full text

Viral Replication, Molecular Virology, Hepatitis C +13

Interdomain Communication in Hepatitis C Virus Polymerase Abolished by Small Molecule Inhibitors Bound to a Novel Allosteric Site

Stefania Di Marco, Cinzia Volpari, Licia Tomei et al. · Journal of Biological Chemistry · 2005 · 162 citations · Full text

Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery of benzimidazole 5-carboxylic amide derivatives with low-nanomolar potency

Pierre L. Beaulieu, Michael Bös, Yves Bousquet et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 90 citations · Full text

Medicine, Non-nucleoside Inhibitors, Antiviral Drug Development +7