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Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery of benzimidazole 5-carboxylic amide derivatives with low-nanomolar potency

Pierre L. Beaulieu, Michael Bös, Yves Bousquet, Patrick DeRoy, Gulrez Fazal, Jean Gauthier, James Gillard, Sylvie Goulet, Ginette McKercher, Marc‐André Poupart,

Bioorganic & Medicinal Chemistry Letters · 2004 · 90 citations · 13 references

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13

Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

Qui‐Lim Choo, George Kuo, Amy J. Weiner et al. · Science · 1989 · 6.9K citations

, , +13

Replication of Subgenomic Hepatitis C Virus RNAs in a Hepatoma Cell Line

Volker Lohmann, Frank Körner, Jan Oliver Koch et al. · Science · 1999 · 2.8K citations

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New coupling reagents in peptide chemistry

Reinhard Knorr, Arnold Trzeciak, Willi Bannwarth et al. · Tetrahedron Letters · 1989 · 986 citations

, , +8

Optimal therapy of hepatitis C

Adrian M. Di Bisceglie, Jay H. Hoofnagle · Hepatology · 2002 · 280 citations

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A Practical Oxone®-Mediated,High-Throughput, Solution-Phase Synthesis of Benzimidazolesfrom 1,2-Phenylenediamines and Aldehydes and its Application toPreparative Scale Synthesis

Pierre L. Beaulieu, Bruno Haché, Elisabeth von Moos · Synthesis · 2003 · 220 citations

, , +13