Concepedia

Discovery of novel 3,6-disubstituted 2-pyridinecarboxamide derivatives as GK activators

Morihiro Mitsuya, Kenji Kamata, Makoto Bamba, Hitomi Watanabe, Yasuhiro Sasaki, Kaori Sasaki, Sumika Ohyama, Hideka Hosaka, Yasufumi Nagata, Jun‐ichi Eiki,

Bioorganic & Medicinal Chemistry Letters · 2009 · 44 citations · 12 references

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12

Allosteric Activators of Glucokinase: Potential Role in Diabetes Therapy

Joseph Grimsby, Ramakanth Sarabu, Wendy L. Corbett et al. · Science · 2003 · 537 citations

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Structural Basis for Allosteric Regulation of the Monomeric Allosteric Enzyme Human Glucokinase

Kenji Kamata, Morihiro Mitsuya, T. Nishimura et al. · Structure · 2004 · 503 citations · Full text

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Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm

Franz M. Matschinsky · Diabetes · 1996 · 154 citations

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A Novel Glucokinase Activator Modulates Pancreatic Islet and Hepatocyte Function

Alexander M. Efanov, David G. Barrett, Martin Brenner et al. · Endocrinology · 2005 · 132 citations · Full text

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An Allosteric Activator of Glucokinase Impairs the Interaction of Glucokinase and Glucokinase Regulatory Protein and Regulates Glucose Metabolism

Mayumi Futamura, Hideka Hosaka, Akito Kadotani et al. · Journal of Biological Chemistry · 2006 · 101 citations · Full text

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