Kinase Suppressor of Ras Is Ceramide-Activated Protein Kinase

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

Steffan N. Ho, Henry D. Hunt, Robert M. Horton et al. · Gene · 1989 · 7.5K citations

Natural Sciences, Genetics, Directed Evolution +6

The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway

Omar A. Coso, M Chiariello, Jin‐Chen Yu et al. · Cell · 1995 · 1.6K citations · Full text

Signal Transduction, Signaling Pathway, Molecular Pathway +8

Differential Activation of ERK and JNK Mitogen-Activated Protein Kinases by Raf-1 and MEKK

Audrey Minden, Anning Lin, Martin McMahon et al. · Science · 1994 · 1.1K citations

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

Sally J. Leevers, Hugh F. Paterson, Christopher J. Marshall · Nature · 1994 · 1K citations

Signal Transduction, Plasma Membrane, Medicine +7

Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

Xianfeng Zhang, Jeffrey Settleman, John Kyriakis et al. · Nature · 1993 · 874 citations

Protein Function, Molecular Regulation, Natural Sciences +8