Quercetin-mediated longevity in Caenorhabditis elegans: Is DAF-16 involved?

Sirtuin activators mimic caloric restriction and delay ageing in metazoans

Jason G. Wood, Blanka Rogina, Siva Lavu et al. · Nature · 2004 · 1.9K citations

Life Sciences, Biochemistry, Genetics +16

<i>daf-16</i> : An HNF-3/forkhead Family Member That Can Function to Double the Life-Span of <i>Caenorhabditis elegans</i>

Kui Lin, Jennie B. Dorman, Aylin R. Rodan et al. · Science · 1997 · 1.5K citations

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Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor

Ao‐Lin Hsu, Coleen T. Murphy, Cynthia Kenyon · Science · 2003 · 1.5K citations

Education, Genetics, Molecular Biology +17

Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling

Kui Lin, Honor Hsin, Natasha Libina et al. · Nature Genetics · 2001 · 1K citations

Life Sciences, Biology, Genetics +12

daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans

Samuel T. Henderson, Thomas E. Johnson · Current Biology · 2001 · 949 citations · Full text

Life Sciences, Developmental Biology, Genetics +13