daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans

Aging: A Theory Based on Free Radical and Radiation Chemistry

Denham Harman · Journal of Gerontology · 1956 · 8.5K citations

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Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor

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RNAi

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The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

Scott Ogg, Suzanne Paradis, S Gottlieb et al. · Nature · 1997 · 2K citations

Life Sciences, Genetics, Molecular Biology +13

<i>daf-16</i> : An HNF-3/forkhead Family Member That Can Function to Double the Life-Span of <i>Caenorhabditis elegans</i>

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