Concepedia

A Methylation-Phosphorylation Switch Determines Sox2 Stability and Function in ESC Maintenance or Differentiation

Fang Lan, Ling Zhang, Wei Wei, Xueling Jin, Ping Wang, Yufeng Tong, Jiwen Li, James X. Du, Jiemin Wong

Molecular Cell · 2014 · 199 citations · 36 references

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36

Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells

Laurie A. Boyer, Tong Ihn Lee, Megan F. Cole et al. · Cell · 2005 · 4.5K citations · Full text

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Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

Hitoshi Niwa, Jun‐ichi Miyazaki, Austin Smith · Nature Genetics · 2000 · 3.6K citations

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Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells

Shinji Masui, Yuhki Nakatake, Yayoi Toyooka et al. · Nature Cell Biology · 2007 · 1.3K citations

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Dissecting self-renewal in stem cells with RNA interference

Natalia Ivanova, Radu Dobrin, Rong Lu et al. · Nature · 2006 · 963 citations

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The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

Jing Wang, Sarah Hevi, Julia K. Kurash et al. · Nature Genetics · 2008 · 813 citations

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