Blood · 2002 · 70 citations · 4 references
Life SciencesCell BiologyMolecular BiologyGene ExpressionGene Expression AnalysisMolecular Cell BiologyBone Marrow MicroenvironmentBone Marrow PhysiologyCell-type Specific Gene ExpressionDifferential Expression AnalysisDifferential Gene Expression AnalysisGene Expression RegulationBone Marrow-derived Mesenchymal Stromal CellsDifferentiation-associated Gene ExpressionStem Cell Gene Regulation
Two human stromal cell lines, HS-5 and HS-27a, represent functionally distinct components of the bone marrow microenvironment.[1][1] [2][2] HS-27a supports cobblestone area formation by early hematopoietic progenitors, whereas HS-5 secretes multiple cytokines that support the proliferation of
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