In vivo therapy of myocardial infarction with mesenchymal stem cells modified with prostaglandin I synthase gene improves cardiac performance in mice

Bone marrow cells regenerate infarcted myocardium

Donald Orlic, Jan Kajstura, Stefano Chimenti et al. · Nature · 2001 · 5.2K citations

Life Sciences, Cell Biology, Physiology +14

Human Mesenchymal Stem Cells Differentiate to a Cardiomyocyte Phenotype in the Adult Murine Heart

Catalin Toma, Mark F. Pittenger, Kevin S. Cahill et al. · Circulation · 2002 · 2.2K citations

Engineering, Cardiology, Cell Biology +14

Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts

Abeel A. Mangi, Nicolas Noiseux, Deling Kong et al. · Nature Medicine · 2003 · 1.5K citations

Engineering, Biotechnology, Cardiology +9

Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals

Farida Djouad, Pascale Louis‐Plence, Claire Bony et al. · Blood · 2003 · 1.2K citations

Life Sciences, Immunology, Oncology +11

Evidence supporting paracrine hypothesis for Akt‐modified mesenchymal stem cell‐mediated cardiac protection and functional improvement

Massimiliano Gnecchi, Huamei He, Nicolas Noiseux et al. · The FASEB Journal · 2006 · 1.1K citations

Life Sciences, Cardiology, Physiology +17