Alcohol, But Not Lipopolysaccharide‐Induced Liver Apoptosis Involves Changes in Intracellular Compartmentalization of Apoptotic Regulators

Abstract

Hepatocytes are to be able to mount an apoptotic response to both intrinsic and extrinsic signals. Alcohol increases liver apoptosis predominantly through an intrinsic signaling pathway while LPS recruits extrinsic signaling pathways.