Chemistry Letters · 1992 · 17 citations · 11 references
Life SciencesBiochemistryMolecular BiologyBiosensorsEnzymologyProtein BiochemistryFluorescence ImagingFluorescence SpectroscopyPeptide AnalysisPeptide ChemistryProteolytic EnzymesProteolytic ProcessingFluorescent LabelsPeptide-based ProbesProtein Fluorescence
Abstract New fluorogenic peptides with efficient quenching group were synthesized and subjected to the action of thermolysin and trypsin. The hydrolysis of the peptide bond resulted in the increase in fluorescence intensity by 50-200-fold of the quenched peptides.
11