Concepedia

Reactive oxygen species activated NLRP3 inflammasomes initiate inflammation in hyperosmolarity stressed human corneal epithelial cells and environment-induced dry eye patients

Qinxiang Zheng, Yueping Ren, Peter S. Reinach, Bing Xiao, Huihui Lu, Yirui Zhu, Jia Qu, Wei Chen

Experimental Eye Research · 2015 · 173 citations · 46 references

DOI

Concepts

References

46

The Inflammasome

Fabio Martinon, Kimberly Burns, Jürg Tschopp · Molecular Cell · 2002 · 6K citations · Full text

A role for mitochondria in NLRP3 inflammasome activation

Rongbin Zhou, Amir S. Yazdi, Philippe Menu et al. · Nature · 2010 · 5.4K citations

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Reliability and Validity of the Ocular Surface Disease Index

Rhett M. Schiffman · Archives of Ophthalmology · 2000 · 3K citations

, , +14

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

Kiichi Nakahira, Jeffrey A. Haspel, Vijay Rathinam et al. · Nature Immunology · 2010 · 3K citations · Full text

, , +15

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

François Ghiringhelli, Lionel Apétoh, Antoine Tesnière et al. · Nature Medicine · 2009 · 1.8K citations · Full text

, , +16