Concepedia

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

Kiichi Nakahira, Jeffrey A. Haspel, Vijay Rathinam, Seon‐Jin Lee, Tamás Dolinay, Hilaire C. Lam, Joshua A. Englert, Marlene Rabinovitch, Manuela Cernadas, Hong Pyo Kim,

Nature Immunology · 2010 · 3K citations · 38 references

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38

Autophagy in the Pathogenesis of Disease

Beth Levine, Guido Kroemer · Cell · 2008 · 7K citations · Full text

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Circulating mitochondrial DAMPs cause inflammatory responses to injury

Qin Zhang, Mustafa Raoof, Yu Chen et al. · Nature · 2010 · 3.7K citations · Full text

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Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

Catherine Dostert, Virginie Pétrilli, Robin van Bruggen et al. · Science · 2008 · 2.7K citations · Full text

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Thioredoxin-interacting protein links oxidative stress to inflammasome activation

Rongbin Zhou, Aubry Tardivel, Bernard Thorens et al. · Nature Immunology · 2009 · 2.7K citations

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Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

Xueping Qu, Jie Yu, Govind Bhagat et al. · Journal of Clinical Investigation · 2003 · 2.2K citations · Full text

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