Concepedia

Syntheses and structure–activity relationships for some triazolyl p38α MAPK inhibitors

Jean-Paul G. Seerden, Gabriela Leusink-Ionescu, Robin Leguijt, Catherine Saccavini, Edith Gelens, Bas Dros, Titia E. Woudenberg-Vrenken, Grietje Molema, Jan A. A. M. Kamps, Richard M. Kellogg

Bioorganic & Medicinal Chemistry Letters · 2014 · 19 citations · 25 references

DOIFull text

Open access

Concepts

References

25

Comprehensive analysis of kinase inhibitor selectivity

Mindy I. Davis, Jeremy P. Hunt, Sanna Herrgård et al. · Nature Biotechnology · 2011 · 2.4K citations · Full text

, , +14

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin‐1

Ana Cuenda, J.B. Rouse, Yair N. Doza et al. · FEBS Letters · 1995 · 2.1K citations

, , +14

Ruthenium-Catalyzed Cycloaddition of Alkynes and Organic Azides

Li Zhang, Xinguo Chen, Peng Xue et al. · Journal of the American Chemical Society · 2005 · 1.1K citations

, , +13

Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity

Theonie Anastassiadis, Sean Deacon, Karthik Devarajan et al. · Nature Biotechnology · 2011 · 926 citations · Full text

, , +16

Click Chemistry In Situ: Acetylcholinesterase as a Reaction Vessel for the Selective Assembly of a Femtomolar Inhibitor from an Array of Building Blocks

Warren G. Lewis, Luke G. Green, Flavio Grynszpan et al. · Angewandte Chemie International Edition · 2002 · 740 citations

, , +16