Oncogenic K-Ras requires activation for enhanced activity

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

Sunil R. Hingorani, Emanuel F. Petricoin, Anirban Maitra et al. · Cancer Cell · 2003 · 2.5K citations · Full text

Medicine, Oncology, Pathology +12

Analysis of lung tumor initiation and progression using conditional expression of oncogenic <i>K-ras</i>

Erica L. Jackson, Nicholas A. Willis, Kim L. Mercer et al. · Genes & Development · 2001 · 2K citations · Full text

Medicine, Cancer Biology, Oncology +17

The Ras-RasGAP Complex: Structural Basis for GTPase Activation and Its Loss in Oncogenic Ras Mutants

Klaus Scheffzek, Mohammad Reza Ahmadian, Wolfgang Kabsch et al. · Science · 1997 · 1.6K citations

Life Sciences, Biochemistry, Molecular Biology +17

Chronic Pancreatitis Is Essential for Induction of Pancreatic Ductal Adenocarcinoma by K-Ras Oncogenes in Adult Mice

Carmen Guerra, Alberto J. Schuhmacher, Marta Cañamero et al. · Cancer Cell · 2007 · 1.2K citations · Full text

Medicine, Cancer Biology, Oncology +9

Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

Carmen Guerra, Nieves Mijimolle, Alma Dhawahir et al. · Cancer Cell · 2003 · 572 citations · Full text

Medicine, Cancer Biology, Oncology +16