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Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression

Johannes Schödel, Chiara Bardella, Lina K. Sciesielski, Jill M. Brown, Christopher W. Pugh, Veronica J. Buckle, Ian Tomlinson, Peter J. Ratcliffe, David R. Mole

Nature Genetics · 2012 · 160 citations · 43 references

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43

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

Jacques Ferlay, Hai‐Rim Shin, Freddie Bray et al. · International Journal of Cancer · 2010 · 21.3K citations

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Michael D. Abràmoff, Paulo Magalhães, Sunanda J. Ram · Utrecht University Repository (Utrecht University) · 2004 · 11.9K citations · Full text

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Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O <sub>2</sub> -Regulated Prolyl Hydroxylation

Panu Jaakkola, David R. Mole, Ya‐Min Tian et al. · Science · 2001 · 5.5K citations

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

Patrick H. Maxwell, Michael S. Wiesener, Gin-Wen Chang et al. · Nature · 1999 · 5.2K citations

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HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O <sub>2</sub> Sensing

Mircea Ivan, Keiichi Kondo, Haifeng Yang et al. · Science · 2001 · 4.7K citations · Full text