Concepedia

Binding of two zinc finger nuclease monomers to two specific sites is required for effective double-strand DNA cleavage

Mala Mani, Jeff Smith, Karthikeyan Kandavelou, Jeremy M Berg, Srinivasan Chandrasegaran

Biochemical and Biophysical Research Communications · 2005 · 93 citations · 33 references

DOI

Concepts

References

33

Zinc Finger-DNA Recognition: Crystal Structure of a Zif268-DNA Complex at 2.1 Å

Nikola P. Pavletich, Carl O. Pabo · Science · 1991 · 2.1K citations

, , +15

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain.

Y G Kim, Srinivasan Chandrasegaran · Proceedings of the National Academy of Sciences · 1996 · 2.1K citations

, , +15

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

Fyodor D. Urnov, Jeffrey C. Miller, Ya-Li Lee et al. · Nature · 2005 · 1.6K citations

, , +9

Targeted Chromosomal Cleavage and Mutagenesis in Drosophila Using Zinc-Finger Nucleases

Marina Bibikova, Kent G. Golic, Dana Carroll · Genetics · 2002 · 858 citations

, , +17

Enhancing Gene Targeting with Designed Zinc Finger Nucleases

Marina Bibikova, Kelly J. Beumer, Jonathan K. Trautman et al. · Science · 2003 · 815 citations

, , +13