Concepedia

Stabilized plasmid-lipid particles for systemic gene therapy

Pat Tam, Myrna A. Monck, D Lee, Olga Ludkovski, E C Leng, Kathy A. Clow, Holger Stark, P Scherrer, Roger W. Graham, Pieter R. Cullis

Gene Therapy · 2000 · 148 citations · 27 references

DOI

Concepts

References

27

PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery

Manfred Ogris, Silvia Brunner, Susanne Schüller et al. · Gene Therapy · 1999 · 1.2K citations

, , +16

Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors.

Alberto Gabizón, Demetrios Papahadjopoulos · Proceedings of the National Academy of Sciences · 1988 · 1.1K citations · Full text

, , +17

Improved DNA: liposome complexes for increased systemic delivery and gene expression

Nancy Smyth Templeton, Danilo D. Lasiç, Peter M. Frederik et al. · Nature Biotechnology · 1997 · 740 citations

, , +16

Systemic Gene Expression After Intravenous DNA Delivery into Adult Mice

Ning Zhu, Denny Liggitt, Yong Liu et al. · Science · 1993 · 720 citations

, , +17

Phospholipid vesicle formation and transmembrane protein incorporation using octyl glucoside

Larry Mimms, Guido A. Zampighi, Yasuhiko Nozaki et al. · Biochemistry · 1981 · 679 citations

, , +17