A novel protein-DNA interaction involved with the CpG dinucleotide at −30 upstream is linked to the DNA methylation mediated transcription silencing of the MAGE-A1 gene

A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma

Pierre van der Bruggen, Catia Traversari, Patrick Chomez et al. · Science · 1991 · 3.5K citations

Life Sciences, Immunology, Oncology +17

DNA Methylation Is the Primary Silencing Mechanism for a Set of Germ Line- and Tumor-Specific Genes with a CpG-Rich Promoter

Charles De Smet, Christophe Lurquin, Bernard Lethé et al. · Molecular and Cellular Biology · 1999 · 594 citations

Medicine, Molecular Biology, Oncology +15

The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation.

Charles De Smet, Olivier De Backer, Isabella Faraoni et al. · Proceedings of the National Academy of Sciences · 1996 · 548 citations

Life Sciences, Molecular Biology, Oncology +10

The DNA-binding specificity of SOX9 and other SOX proteins

Sabine Mertin · Nucleic Acids Research · 1999 · 232 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

The JUN oncoprotein, a vertebrate transcription factor, activates transcription in yeast

Kevin Struhl · Nature · 1988 · 178 citations

Medicine, Genetics, Molecular Biology +14