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Exon-Junction Complex Components Specify Distinct Routes of Nonsense-Mediated mRNA Decay with Differential Cofactor Requirements

Niels H. Gehring, Joachim B. Kunz, Gabriele Neu‐Yilik, Stephen Breit, Marcelo H. Viegas, Matthias W. Hentze, Andreas E. Kulozik

Molecular Cell · 2005 · 330 citations · 29 references

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29

Expression profiling reveals off-target gene regulation by RNAi

Aimee L. Jackson, Steven R. Bartz, Janell M. Schelter et al. · Nature Biotechnology · 2003 · 2.4K citations

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The spliceosome deposits multiple proteins 20–24 nucleotides upstream of mRNA exon–exon junctions

Hervé Le Hir · The EMBO Journal · 2000 · 953 citations · Full text

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Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise

Joshua T. Mendell, Neda Sharifi, Jennifer Meyers et al. · Nature Genetics · 2004 · 877 citations

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The exon–exon junction complex provides a binding platform for factors involved in mRNA export and nonsense‐mediated mRNA decay

Hervé Le Hir · The EMBO Journal · 2001 · 828 citations · Full text

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Human Upf Proteins Target an mRNA for Nonsense-Mediated Decay When Bound Downstream of a Termination Codon

Jens Lykke‐Andersen, Mei-Di Shu, Joan A. Steitz · Cell · 2000 · 582 citations · Full text

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