Human Upf Proteins Target an mRNA for Nonsense-Mediated Decay When Bound Downstream of a Termination Codon

Overexpression of HuR, a nuclear–cytoplasmic shuttling protein, increases the in vivo stability of ARE‐containing mRNAs

The EMBO Journal · 1998 · 871 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm

S Piñol-Roma, Gideon Dreyfuss · Nature · 1992 · 836 citations

Life Sciences, Cell Biology, Molecular Biology +12

When cells stop making sense: effects of nonsense codons on RNA metabolism in vertebrate cells.

Lynne E. Maquat · PubMed · 1995 · 514 citations

Life Sciences, Molecular Biology, Molecular Genetics +17

The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon.

Peter Leeds, Stuart W. Peltz, Allan Jacobson et al. · Genes & Development · 1991 · 502 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

mRNA surveillance by the Caenorhabditis elegans smg genes.

Rock Pulak, Philip Anderson · Genes & Development · 1993 · 468 citations · Full text

Life Sciences, Biology, Genetics +17