Human Upf Proteins Target an mRNA for Nonsense-Mediated Decay When Bound Downstream of a Termination Codon

Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the invivo stability of ARE-containing mRNAs

Xiucai Fan · The EMBO Journal · 1998 · 868 citations · Full text

Chromatin, Are-containing Mrnas, Nuclear-cytoplasmic Shuttling Protein +10

Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm

S Piñol-Roma, Gideon Dreyfuss · Nature · 1992 · 832 citations

Transcriptional Regulation, Rna Binding Proteins, Rna Biology +5

When cells stop making sense: effects of nonsense codons on RNA metabolism in vertebrate cells.

Lynne E. Maquat · PubMed · 1995 · 514 citations

Genetics, Rna Processing, Rna Metabolism +16

The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon.

Peter Leeds, Stuart W. Peltz, Allan Jacobson et al. · Genes & Development · 1991 · 495 citations · Full text

mRNA surveillance by the Caenorhabditis elegans smg genes.

Rock Pulak, Philip Anderson · Genes & Development · 1993 · 462 citations · Full text

Transcriptional Regulation, Systems Biology, Engineering +14