Lymphoid tyrosine phosphatase (LYP/PTPN22) Arg620Trp variant regulates insulin autoimmunity and progression to type 1 diabetes

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Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

Hironori Ueda, Joanna M. M. Howson, Laura Esposito et al. · Nature · 2003 · 2.2K citations

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A Missense Single-Nucleotide Polymorphism in a Gene Encoding a Protein Tyrosine Phosphatase (PTPN22) Is Associated with Rheumatoid Arthritis

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A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

Nunzio Bottini, Lucia Musumeci, Andrés Alonso et al. · Nature Genetics · 2004 · 1.4K citations

Medicine, Biochemistry, Endocrinology +13

Pathologic Anatomy of the Pancreas in Juvenile Diabetes Mellitus

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Medicine, Endocrinology, Pathology +17