Concepedia

Gene polymorphisms in pattern recognition receptors and susceptibility to idiopathic recurrent vulvovaginal candidiasis

Diana C. Rosentul, Corine Delsing, Martin Jaeger, Theo S. Plantinga, Marije Oosting, Irene Costantini, Hanka Venselaar, Leo A. B. Joosten, J.W.M. van der Meer, B. Dupont,

Frontiers in Microbiology · 2014 · 87 citations · 36 references

DOIFull text

Open access

Abstract

Genetic variation in TLR2 may significantly enhance susceptibility to RVVC by modulating host defense mechanisms against Candida. Additional studies are warranted to assess systematically the role of host genetic variation for susceptibility to RVVC.

References

36

SIFT: predicting amino acid changes that affect protein function

P.C. Ng · Nucleic Acids Research · 2003 · 6.7K citations · Full text

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PANTHER: A Library of Protein Families and Subfamilies Indexed by Function

Paul D. Thomas, Michael J. Campbell, Anish Kejariwal et al. · Genome Research · 2003 · 3K citations · Full text

Collaborative Induction of Inflammatory Responses by Dectin-1 and Toll-like Receptor 2

Benjamin N. Gantner, Randi M. Simmons, Scott J. Canavera et al. · The Journal of Experimental Medicine · 2003 · 1.6K citations · Full text

Increasing the precision of comparative models with YASARA NOVA—a self‐parameterizing force field

Elmar Krieger, Günther Koraimann, Gert Vriend · Proteins Structure Function and Bioinformatics · 2002 · 1.5K citations · Full text

Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide

Mi Sun Jin, Sung Eun Kim, Jin Young Heo et al. · Cell · 2007 · 1.3K citations · Full text

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